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Binding of Rap1 and Riam to Talin1 Fine-Tune β2 Integrin Activity During Leukocyte Trafficking

β2 integrins mediate key processes during leukocyte trafficking. Upon leukocyte activation, the structurally bent β2 integrins change their conformation towards an extended, intermediate and eventually high affinity conformation, which mediate slow leukocyte rolling and firm arrest, respectively. Tr...

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Detalles Bibliográficos
Autores principales: Bromberger, Thomas, Klapproth, Sarah, Rohwedder, Ina, Weber, Jasmin, Pick, Robert, Mittmann, Laura, Min-Weißenhorn, Soo Jin, Reichel, Christoph A., Scheiermann, Christoph, Sperandio, Markus, Moser, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417109/
https://www.ncbi.nlm.nih.gov/pubmed/34489950
http://dx.doi.org/10.3389/fimmu.2021.702345