Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model

Myotonic dystrophy type 1 (DM1) is an inherited neuromuscular disease caused by expanded CTG repeats in the 3′ untranslated region (3′UTR) of the DMPK gene. The myogenesis process is defective in DM1, which is closely associated with progressive muscle weakness and wasting. Despite many proposed exp...

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Detalles Bibliográficos
Autores principales: Shen, Xiaopeng, Liu, Zhongxian, Wang, Chunguang, Xu, Feng, Zhang, Jingyi, Li, Meng, Lei, Yang, Wang, Ao, Bi, Chao, Zhu, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417118/
https://www.ncbi.nlm.nih.gov/pubmed/34490258
http://dx.doi.org/10.3389/fcell.2021.710112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417118/
https://www.ncbi.nlm.nih.gov/pubmed/34490258
http://dx.doi.org/10.3389/fcell.2021.710112

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