Aberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy

In a previous study, we showed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinoma (VSCC). In this study, we further validated our findings on a prospective cohort of primary VSCC cases, where immunohistochemical staining confirmed that key Hh pathway...

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Detalles Bibliográficos
Autores principales: Yap, Jason K. W., Uddin, Khalil, Pounds, Rachel, O’Neill, Danielle, Kehoe, Sean, Ganesan, Raji, Dawson, Christopher W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417215/
https://www.ncbi.nlm.nih.gov/pubmed/34480080
http://dx.doi.org/10.1038/s41598-021-96940-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417215/
https://www.ncbi.nlm.nih.gov/pubmed/34480080
http://dx.doi.org/10.1038/s41598-021-96940-1

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