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Aberrant activation of the Hedgehog signalling pathway in squamous cell carcinoma of the vulva as a potential target for cancer therapy
In a previous study, we showed that the Hedgehog (Hh) signalling pathway is aberrantly activated in vulval squamous cell carcinoma (VSCC). In this study, we further validated our findings on a prospective cohort of primary VSCC cases, where immunohistochemical staining confirmed that key Hh pathway...
Autores principales: | Yap, Jason K. W., Uddin, Khalil, Pounds, Rachel, O’Neill, Danielle, Kehoe, Sean, Ganesan, Raji, Dawson, Christopher W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417215/ https://www.ncbi.nlm.nih.gov/pubmed/34480080 http://dx.doi.org/10.1038/s41598-021-96940-1 |
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