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C-type lectin receptor Dectin3 deficiency balances the accumulation and function of FoxO1-mediated LOX-1(+) M-MDSCs in relieving lupus-like symptoms

Recent studies indicate that Toll-like receptors (TLRs) and C-type lectin receptors (CLRs) can function as the signal of pattern recognition receptors, which play a pivotal role in the pathogenesis of the autoimmune disease. Systemic lupus erythematosus (SLE) is a classic autoimmune disease. Previou...

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Detalles Bibliográficos
Autores principales: Li, Dan, Lu, Li, Kong, Wei, Xia, Xiaoyu, Pan, Yuchen, Li, Jingman, Wang, Jiali, Wang, Tingting, Liang, Jun, Dou, Huan, Hou, Yayi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417277/
https://www.ncbi.nlm.nih.gov/pubmed/34480018
http://dx.doi.org/10.1038/s41419-021-04052-5