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A Bayesian approach for accurate de novo transcriptome assembly

De novo transcriptome assembly from billions of RNA-seq reads is very challenging due to alternative splicing and various levels of expression, which often leads to incorrect, mis-assembled transcripts. BayesDenovo addresses this problem by using both a read-guided strategy to accurately reconstruct...

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Detalles Bibliográficos
Autores principales: Shi, Xu, Wang, Xiao, Neuwald, Andrew F., Halakivi-Clarke, Leena, Clarke, Robert, Xuan, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417280/
https://www.ncbi.nlm.nih.gov/pubmed/34480063
http://dx.doi.org/10.1038/s41598-021-97015-x