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Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease

Diabetes mellitus is a metabolic disease associated with dysregulated glucose and insulin levels and an increased risk of developing Alzheimer’s disease (AD) later in life. It is thought that chronic hyperglycemia leads to neuroinflammation and tau hyperphosphorylation in the hippocampus leading to...

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Detalles Bibliográficos
Autores principales: Wirt, Ryan. A., Crew, Lauren. A., Ortiz, Andrew. A., McNeela, Adam. M., Flores, Emmanuel, Kinney, Jefferson. W., Hyman, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417282/
https://www.ncbi.nlm.nih.gov/pubmed/34480097
http://dx.doi.org/10.1038/s42003-021-02558-4