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Altered theta rhythm and hippocampal-cortical interactions underlie working memory deficits in a hyperglycemia risk factor model of Alzheimer’s disease
Diabetes mellitus is a metabolic disease associated with dysregulated glucose and insulin levels and an increased risk of developing Alzheimer’s disease (AD) later in life. It is thought that chronic hyperglycemia leads to neuroinflammation and tau hyperphosphorylation in the hippocampus leading to...
Autores principales: | Wirt, Ryan. A., Crew, Lauren. A., Ortiz, Andrew. A., McNeela, Adam. M., Flores, Emmanuel, Kinney, Jefferson. W., Hyman, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417282/ https://www.ncbi.nlm.nih.gov/pubmed/34480097 http://dx.doi.org/10.1038/s42003-021-02558-4 |
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