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Strategy for Leukemia Treatment Targeting SHP-1,2 and SHIP

Protein tyrosine phosphatases (PTPs) are modulators of cellular functions such as differentiation, metabolism, migration, and survival. PTPs antagonize tyrosine kinases by removing phosphate moieties from molecular signaling residues, thus inhibiting signal transduction. Two PTPs, SHP-1 and SHP-2 (S...

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Detalles Bibliográficos
Autores principales: Hao, Fang, Wang, Chen, Sholy, Christine, Cao, Min, Kang, Xunlei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417302/
https://www.ncbi.nlm.nih.gov/pubmed/34490276
http://dx.doi.org/10.3389/fcell.2021.730400