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Strategy for Leukemia Treatment Targeting SHP-1,2 and SHIP
Protein tyrosine phosphatases (PTPs) are modulators of cellular functions such as differentiation, metabolism, migration, and survival. PTPs antagonize tyrosine kinases by removing phosphate moieties from molecular signaling residues, thus inhibiting signal transduction. Two PTPs, SHP-1 and SHP-2 (S...
Autores principales: | Hao, Fang, Wang, Chen, Sholy, Christine, Cao, Min, Kang, Xunlei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417302/ https://www.ncbi.nlm.nih.gov/pubmed/34490276 http://dx.doi.org/10.3389/fcell.2021.730400 |
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