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Combining Immunocytokine and Ex Vivo Activated NK Cells as a Platform for Enhancing Graft-Versus-Tumor Effects Against GD2(+) Murine Neuroblastoma

Management for high-risk neuroblastoma (NBL) has included autologous hematopoietic stem cell transplant (HSCT) and anti-GD2 immunotherapy, but survival remains around 50%. The aim of this study was to determine if allogeneic HSCT could serve as a platform for inducing a graft-versus-tumor (GVT) effe...

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Detalles Bibliográficos
Autores principales: Bates, Paul D., Rakhmilevich, Alexander L., Cho, Monica M., Bouchlaka, Myriam N., Rao, Seema L., Hales, Joanna M., Orentas, Rimas J., Fry, Terry J., Gilles, Stephen D., Sondel, Paul M., Capitini, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417312/
https://www.ncbi.nlm.nih.gov/pubmed/34489927
http://dx.doi.org/10.3389/fimmu.2021.668307