Charcoal Hemoperfusion for Methotrexate Toxicity: A Safe and Effective Life-Rescue Alternative When Glucarpidase Is Not Available

Background: High dose methotrexate (HDMTX) is used for the treatment of pediatric hemato-oncological diseases. HDMTX can induce acute kidney injury in cases of delayed elimination. The use of leucovorin remains the most effective rescue action. Further treatment options are of difficult access in th...

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Detalles Bibliográficos
Autores principales: Rosales, Alejandra, Madrid, Alvaro, Muñoz, Marina, Dapena, Jose Luis, Ariceta, Gema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417363/
https://www.ncbi.nlm.nih.gov/pubmed/34490152
http://dx.doi.org/10.3389/fped.2021.635152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417363/
https://www.ncbi.nlm.nih.gov/pubmed/34490152
http://dx.doi.org/10.3389/fped.2021.635152

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