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Proviral Turnover During Untreated HIV Infection Is Dynamic and Variable Between Hosts, Impacting Reservoir Composition on ART

Human immunodeficiency virus (HIV) can persist as an integrated provirus, in a transcriptionally repressed state, within infected cells. This small yet enduring pool of cellular reservoirs that harbor replication-competent HIV is the main barrier to cure. Entry of viral sequences into cellular reser...

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Detalles Bibliográficos
Autores principales: Brooks, Kelsie, Omondi, F. Harrison, Liang, Richard H., Sudderuddin, Hanwei, Jones, Bradley R., Joy, Jeffrey B., Brumme, Chanson J., Hunter, Eric, Brumme, Zabrina L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417368/
https://www.ncbi.nlm.nih.gov/pubmed/34489909
http://dx.doi.org/10.3389/fmicb.2021.719153