Antisense oligonucleotide–mediated inhibition of angiopoietin-like protein 3 increases reverse cholesterol transport in mice

Supported by an abundance of experimental and genetic evidence, angiopoietin-like protein 3 (ANGPTL3) has emerged as a promising therapeutic target for cardiovascular disease. ANGPTL3 is primarily produced by the liver and is a potent modulator of plasma lipids and lipoproteins. Experimental models...

Descripción completa

Detalles Bibliográficos
Autores principales: Bell, Thomas A., Liu, Mingxia, Donner, Aaron J., Lee, Richard G., Mullick, Adam E., Crooke, Rosanne M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417398/
https://www.ncbi.nlm.nih.gov/pubmed/34371033
http://dx.doi.org/10.1016/j.jlr.2021.100101

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417398/
https://www.ncbi.nlm.nih.gov/pubmed/34371033
http://dx.doi.org/10.1016/j.jlr.2021.100101

Ejemplares similares