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L-3,4-Dihydroxyphenylalanine Recovers Circadian Rhythm Disturbances in the Rat Models of Parkinson's Disease by Regulating the D1R-ERK1/2-mTOR Pathway
Objective: Patients with Parkinson's disease (PD) frequently experience disruptions in the 24-h daily profile of both behavioral and biological markers. However, whether L-3,4-dihydroxyphenylalanine (L-dopa) influences these markers associated with circadian rhythm or not is still an open quest...
Autores principales: | Yang, Shuyuan, Wan, Ying, Wu, Na, Song, Lu, Liu, Zhihua, Zhao, Jiahao, Liu, Ying, Liu, Zhenguo, Gan, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417416/ https://www.ncbi.nlm.nih.gov/pubmed/34489685 http://dx.doi.org/10.3389/fnagi.2021.719885 |
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