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Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer

Oxaliplatin resistance is a challenge in the treatment of colorectal cancer (CRC) patients. Regulatory T cells (Tregs) are well known for their immunosuppressive roles, and targeting Tregs is an effective way to improve chemosensitivity. Exosome-delivered microRNA (miRNA) might be used as a potentia...

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Detalles Bibliográficos
Autores principales: Ning, Tao, Li, Jialu, He, Yi, Zhang, Haiyang, Wang, Xinyi, Deng, Ting, Liu, Rui, Li, Hongli, Bai, Ming, Fan, Qian, Zhu, Kegan, Ying, Guoguang, Ba, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417448/
https://www.ncbi.nlm.nih.gov/pubmed/33905821
http://dx.doi.org/10.1016/j.ymthe.2021.04.028