CAR- and TRuC-redirected regulatory T cells differ in capacity to control adaptive immunity to FVIII

Regulatory T cells (Tregs) control immune responses in autoimmune disease, transplantation, and enable antigen-specific tolerance induction in protein-replacement therapies. Tregs can exert a broad array of suppressive functions through their T cell receptor (TCR) in a tissue-directed and antigen-sp...

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Detalles Bibliográficos
Autores principales: Rana, Jyoti, Perry, Daniel J., Kumar, Sandeep R.P., Muñoz-Melero, Maite, Saboungi, Rania, Brusko, Todd M., Biswas, Moanaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417451/
https://www.ncbi.nlm.nih.gov/pubmed/33940160
http://dx.doi.org/10.1016/j.ymthe.2021.04.034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417451/
https://www.ncbi.nlm.nih.gov/pubmed/33940160
http://dx.doi.org/10.1016/j.ymthe.2021.04.034

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