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High-throughput quantitation method for amodiaquine and desethylamodiaquine in plasma using supported liquid extraction technology

Amodiaquine is a drug used for treatment of malaria and is often used in combination with artesunate in areas where malaria parasites are still susceptible to amodiaquine. Liquid chromatography tandem-mass spectrometry was used to quantify amodiaquine and its active metabolite, desethylamodiaquine,...

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Detalles Bibliográficos
Autores principales: Kaewkhao, Karnrawee, Tarning, Joel, Blessborn, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417464/
https://www.ncbi.nlm.nih.gov/pubmed/34364298
http://dx.doi.org/10.1016/j.jchromb.2021.122887