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Packpred: Predicting the Functional Effect of Missense Mutations

Predicting the functional consequences of single point mutations has relevance to protein function annotation and to clinical analysis/diagnosis. We developed and tested Packpred that makes use of a multi-body clique statistical potential in combination with a depth-dependent amino acid substitution...

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Detalles Bibliográficos
Autores principales: Tan, Kuan Pern, Kanitkar, Tejashree Rajaram, Kwoh, Chee Keong, Madhusudhan, Mallur Srivatsan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417552/
https://www.ncbi.nlm.nih.gov/pubmed/34490344
http://dx.doi.org/10.3389/fmolb.2021.646288