Targeting the Urokinase-Type Plasminogen Activator Receptor (uPAR) in Human Diseases With a View to Non-invasive Imaging and Therapeutic Intervention

The interaction between the serine protease urokinase-type plasminogen activator (uPA) and its glycolipid-anchored receptor (uPAR) focalizes plasminogen activation to cell surfaces, thereby regulating extravascular fibrinolysis, cell adhesion, and migration. uPAR belongs to the Ly6/uPAR (LU) gene su...

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Detalles Bibliográficos
Autores principales: Leth, Julie Maja, Ploug, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417595/
https://www.ncbi.nlm.nih.gov/pubmed/34490277
http://dx.doi.org/10.3389/fcell.2021.732015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417595/
https://www.ncbi.nlm.nih.gov/pubmed/34490277
http://dx.doi.org/10.3389/fcell.2021.732015

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