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Beyond the Driver Mutation: Immunotherapies in Gastrointestinal Stromal Tumors

Gastrointestinal stromal tumors (GISTs) are a subtype of soft tissue sarcoma (STS), and have become a concept of oncogenic addiction and targeted therapies.The large majority of these tumors develop after a mutation in KIT or platelet derived growth factor receptor α (PDGFRα), resulting in uncontrol...

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Detalles Bibliográficos
Autores principales: Roulleaux Dugage, Matthieu, Jones, Robin Lewis, Trent, Jonathan, Champiat, Stéphane, Dumont, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417712/
https://www.ncbi.nlm.nih.gov/pubmed/34489967
http://dx.doi.org/10.3389/fimmu.2021.715727