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Beyond the Driver Mutation: Immunotherapies in Gastrointestinal Stromal Tumors
Gastrointestinal stromal tumors (GISTs) are a subtype of soft tissue sarcoma (STS), and have become a concept of oncogenic addiction and targeted therapies.The large majority of these tumors develop after a mutation in KIT or platelet derived growth factor receptor α (PDGFRα), resulting in uncontrol...
Autores principales: | Roulleaux Dugage, Matthieu, Jones, Robin Lewis, Trent, Jonathan, Champiat, Stéphane, Dumont, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417712/ https://www.ncbi.nlm.nih.gov/pubmed/34489967 http://dx.doi.org/10.3389/fimmu.2021.715727 |
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