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Serum proBDNF Is Associated With Changes in the Ketone Body β-Hydroxybutyrate and Shows Superior Repeatability Over Mature BDNF: Secondary Outcomes From a Cross-Over Trial in Healthy Older Adults

Background: β-hydroxybutyrate (BHB) can upregulate brain-derived neurotrophic factor (BDNF) in mice, but little is known about the associations between BHB and BDNF in humans. The primary aim here was to investigate whether ketosis (i.e., raised BHB levels), induced by a ketogenic supplement, influe...

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Detalles Bibliográficos
Autores principales: Norgren, Jakob, Daniilidou, Makrina, Kåreholt, Ingemar, Sindi, Shireen, Akenine, Ulrika, Nordin, Karin, Rosenborg, Staffan, Ngandu, Tiia, Kivipelto, Miia, Sandebring-Matton, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417778/
https://www.ncbi.nlm.nih.gov/pubmed/34489682
http://dx.doi.org/10.3389/fnagi.2021.716594