Nucleolipid Acid-Based Nanocarriers Restore Neuronal Lysosomal Acidification Defects

Increasing evidence suggests that lysosomal dysfunction has a pathogenic role in neurodegenerative diseases. In particular, an increase in lysosomal pH has been reported in different cellular models of Parkinson’s disease. Thus, targeting lysosomes has emerged as a promising approach. More specifica...

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Detalles Bibliográficos
Autores principales: Brouillard, Mathias, Barthélémy, Philippe, Dehay, Benjamin, Crauste-Manciet, Sylvie, Desvergnes, Valérie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417785/
https://www.ncbi.nlm.nih.gov/pubmed/34490217
http://dx.doi.org/10.3389/fchem.2021.736554

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417785/
https://www.ncbi.nlm.nih.gov/pubmed/34490217
http://dx.doi.org/10.3389/fchem.2021.736554

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