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Autologous Dendritic Cells in Combination With Chemotherapy Restore Responsiveness of T Cells in Breast Cancer Patients: A Single-Arm Phase I/II Trial

INTRODUCTION: Animal studies and preclinical studies in cancer patients suggest that the induction of immunogenic cell death (ICD) by neoadjuvant chemotherapy with doxorubicin and cyclophosphamide (NAC-AC) recovers the functional performance of the immune system. This could favor immunotherapy schem...

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Detalles Bibliográficos
Autores principales: Bernal-Estévez, David A., Ortíz Barbosa, Mauren A., Ortíz-Montero, Paola, Cifuentes, Claudia, Sánchez, Ramiro, Parra-López, Carlos A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417880/
https://www.ncbi.nlm.nih.gov/pubmed/34489928
http://dx.doi.org/10.3389/fimmu.2021.669965