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Autologous Dendritic Cells in Combination With Chemotherapy Restore Responsiveness of T Cells in Breast Cancer Patients: A Single-Arm Phase I/II Trial
INTRODUCTION: Animal studies and preclinical studies in cancer patients suggest that the induction of immunogenic cell death (ICD) by neoadjuvant chemotherapy with doxorubicin and cyclophosphamide (NAC-AC) recovers the functional performance of the immune system. This could favor immunotherapy schem...
Autores principales: | Bernal-Estévez, David A., Ortíz Barbosa, Mauren A., Ortíz-Montero, Paola, Cifuentes, Claudia, Sánchez, Ramiro, Parra-López, Carlos A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417880/ https://www.ncbi.nlm.nih.gov/pubmed/34489928 http://dx.doi.org/10.3389/fimmu.2021.669965 |
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