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Microglial TREM2 Mitigates Inflammatory Responses and Neuronal Apoptosis in Angiotensin II-Induced Hypertension in Middle-Aged Mice

Growing evidence suggests that hypertension and aging are prominent risk factors for the development of late-onset Alzheimer’s disease (LOAD) by inducement of neuroinflammation. Recent study showed that neuroinflammation via activated microglia induces reactive astrocytes, termed A1 astrocytes, that...

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Detalles Bibliográficos
Autores principales: Xu, Xiaotian, Du, Lin, Jiang, Jianxiong, Yang, Ming, Wang, Zhaoxia, Wang, Yingge, Tang, Tieyu, Fu, Xuetao, Hao, Jiukuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417947/
https://www.ncbi.nlm.nih.gov/pubmed/34489683
http://dx.doi.org/10.3389/fnagi.2021.716917