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Microglial TREM2 Mitigates Inflammatory Responses and Neuronal Apoptosis in Angiotensin II-Induced Hypertension in Middle-Aged Mice
Growing evidence suggests that hypertension and aging are prominent risk factors for the development of late-onset Alzheimer’s disease (LOAD) by inducement of neuroinflammation. Recent study showed that neuroinflammation via activated microglia induces reactive astrocytes, termed A1 astrocytes, that...
Autores principales: | Xu, Xiaotian, Du, Lin, Jiang, Jianxiong, Yang, Ming, Wang, Zhaoxia, Wang, Yingge, Tang, Tieyu, Fu, Xuetao, Hao, Jiukuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417947/ https://www.ncbi.nlm.nih.gov/pubmed/34489683 http://dx.doi.org/10.3389/fnagi.2021.716917 |
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