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Topical gel based nanoparticles for the controlled release of oleanolic acid: design and in vivo characterization of a cubic liquid crystalline anti-inflammatory drug

BACKGROUND: Oleanolic acid (OA) has multiple pharmaceutical applications including anti-inflammatory activity, but low permeability of the molecule limits its widespread use. METHODS: A cubic liquid crystalline nanoparticle (LCNP)-based gel was prepared as a potential topical delivery system for OA....

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Detalles Bibliográficos
Autores principales: Shi, Zhiqi, Pan, Shugang, Wang, Luolin, Li, Sha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8417955/
https://www.ncbi.nlm.nih.gov/pubmed/34481504
http://dx.doi.org/10.1186/s12906-021-03399-8