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Head and neck squamous cell carcinoma cell lines have an immunomodulatory effect on macrophages independent of hypoxia and toll-like receptor 9

BACKGROUND: A low tissue oxygen level, < 1% O(2), is a typical characteristic inside of solid tumors in head and neck cancer (HNSCC) affecting a wide array of cell populations, such as macrophages. However, the mechanisms of how hypoxia influences macrophages are not yet fully elucidated. Our res...

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Detalles Bibliográficos
Autores principales: Ishizu, Tamiko, Eichin, Dominik, Padzik, Artur, Tuominen, Sanni, Grénman, Reidar, Salmi, Marko, Grönroos, Tove J., Tuomela, Johanna M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418007/
https://www.ncbi.nlm.nih.gov/pubmed/34479492
http://dx.doi.org/10.1186/s12885-021-08357-8