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Therapeutic potential of a novel semi-synthetic-sulfated-polysaccharide to suppress inflammatory mediators in P. gingivalis LPS stimulated human monocytes/macrophages

BACKGROUND: Chronic periodontitis is associated with an increased risk for systemic conditions such as cardiovascular disease, diabetes, and osteoporosis. During chronic periodontitis, endotoxin (lipopolysaccharide, LPS) produced by P. gingivalis provokes monocyte accumulation and differentiation in...

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Detalles Bibliográficos
Autores principales: Gu, Ying, Raja, Veena, Lee, Hsi-Ming, Hong, Houlin, Prestwich, Glenn, Ryan, Maria E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418013/
https://www.ncbi.nlm.nih.gov/pubmed/34481488
http://dx.doi.org/10.1186/s12950-021-00292-6