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Binding of Staphylococcal Enterotoxin B (SEB) to B7 Receptors Triggers TCR- and CD28-Mediated Inflammatory Signals in the Absence of MHC Class II Molecules

The inflammatory activity of staphylococcal enterotoxin B (SEB) relies on its capacity to trigger polyclonal T-cell activation by binding both T-cell receptor (TCR) and costimulatory receptor CD28 on T cells and MHC class II and B7 molecules on antigen presenting cells (APC). Previous studies highli...

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Detalles Bibliográficos
Autores principales: Kunkl, Martina, Amormino, Carola, Caristi, Silvana, Tedeschi, Valentina, Fiorillo, Maria Teresa, Levy, Revital, Popugailo, Andrey, Kaempfer, Raymond, Tuosto, Loretta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418141/
https://www.ncbi.nlm.nih.gov/pubmed/34489975
http://dx.doi.org/10.3389/fimmu.2021.723689