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Endoglin-Aptamer-Functionalized Liposome-Equipped PD-1-Silenced T Cells Enhance Antitumoral Immunotherapeutic Effects

BACKGROUND: The broader application of adoptive cell therapy (ACT) in cancer immunotherapies (particularly for solid tumors) has always been limited by the immunosuppressive tumor microenvironment (TME) and the insufficient targetability of effector T cells, resulting in unsatisfied therapeutic outc...

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Detalles Bibliográficos
Autores principales: Xie, Shenxia, Hou, Xiaoqiong, Yang, Wei, Shi, Wei, Yang, Xiaomei, Duan, Siliang, Mo, Fengzhen, Liu, Aiqun, Wang, Wu, Lu, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418331/
https://www.ncbi.nlm.nih.gov/pubmed/34511903
http://dx.doi.org/10.2147/IJN.S317220