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Endoglin-Aptamer-Functionalized Liposome-Equipped PD-1-Silenced T Cells Enhance Antitumoral Immunotherapeutic Effects
BACKGROUND: The broader application of adoptive cell therapy (ACT) in cancer immunotherapies (particularly for solid tumors) has always been limited by the immunosuppressive tumor microenvironment (TME) and the insufficient targetability of effector T cells, resulting in unsatisfied therapeutic outc...
Autores principales: | Xie, Shenxia, Hou, Xiaoqiong, Yang, Wei, Shi, Wei, Yang, Xiaomei, Duan, Siliang, Mo, Fengzhen, Liu, Aiqun, Wang, Wu, Lu, Xiaoling |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418331/ https://www.ncbi.nlm.nih.gov/pubmed/34511903 http://dx.doi.org/10.2147/IJN.S317220 |
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