Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction

Axonal Charcot-Marie-Tooth neuropathies (CMT type 2) are caused by inherited mutations in various genes functioning in different pathways. The types of genes and multiplicity of mutations reflect the clinical and genetic heterogeneity in CMT2 disease, which complicates its diagnosis and has inhibite...

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Detalles Bibliográficos
Autores principales: Van Lent, Jonas, Verstraelen, Peter, Asselbergh, Bob, Adriaenssens, Elias, Mateiu, Ligia, Verbist, Christophe, De Winter, Vicky, Eggermont, Kristel, Van Den Bosch, Ludo, De Vos, Winnok H, Timmerman, Vincent
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418338/
https://www.ncbi.nlm.nih.gov/pubmed/34128983
http://dx.doi.org/10.1093/brain/awab226

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418338/
https://www.ncbi.nlm.nih.gov/pubmed/34128983
http://dx.doi.org/10.1093/brain/awab226

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