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METTL3‐mediated m6A methylation of ASPM drives hepatocellular carcinoma cells growth and metastasis

BACKGROUND: Abnormal spindle‐like microcephaly (ASPM) has been proved to participate in tumor progression. However, the underlying mechanism of ASPM in liver hepatocellular carcinoma (LIHC) remains elusive. METHODS: The mRNA and protein expression were determined using Western blot and qRT‐PCR, and...

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Detalles Bibliográficos
Autores principales: Wang, An, Chen, Xiaofeng, Li, Dongen, Yang, Liang, Jiang, Jianshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418466/
https://www.ncbi.nlm.nih.gov/pubmed/34398984
http://dx.doi.org/10.1002/jcla.23931