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METTL3‐mediated m6A methylation of ASPM drives hepatocellular carcinoma cells growth and metastasis
BACKGROUND: Abnormal spindle‐like microcephaly (ASPM) has been proved to participate in tumor progression. However, the underlying mechanism of ASPM in liver hepatocellular carcinoma (LIHC) remains elusive. METHODS: The mRNA and protein expression were determined using Western blot and qRT‐PCR, and...
Autores principales: | Wang, An, Chen, Xiaofeng, Li, Dongen, Yang, Liang, Jiang, Jianshuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418466/ https://www.ncbi.nlm.nih.gov/pubmed/34398984 http://dx.doi.org/10.1002/jcla.23931 |
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