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Correcting Artifacts in Ratiometric Biosensor Imaging; an Improved Approach for Dividing Noisy Signals

The accuracy of biosensor ratio imaging is limited by signal/noise. Signals can be weak when biosensor concentrations must be limited to avoid cell perturbation. This can be especially problematic in imaging of low volume regions, e.g., along the cell edge. The cell edge is an important imaging targ...

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Detalles Bibliográficos
Autores principales: Marston, Daniel J., Slattery, Scott D., Hahn, Klaus M., Tsygankov, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418531/
https://www.ncbi.nlm.nih.gov/pubmed/34490242
http://dx.doi.org/10.3389/fcell.2021.685825