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Non-apoptotic function of caspase-8 confers prostate cancer enzalutamide resistance via NF-κB activation
Caspase-8 is a unique member of caspases with a dual role in cell death and survival. Caspase-8 expression is often lost in some tumors, but increased in others, indicating a potential pro-survival function in cancer. By analyzing transcriptome of enzalutamide-resistant prostate cancer cells, we fou...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418603/ https://www.ncbi.nlm.nih.gov/pubmed/34482382 http://dx.doi.org/10.1038/s41419-021-04126-4 |