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Non-apoptotic function of caspase-8 confers prostate cancer enzalutamide resistance via NF-κB activation

Caspase-8 is a unique member of caspases with a dual role in cell death and survival. Caspase-8 expression is often lost in some tumors, but increased in others, indicating a potential pro-survival function in cancer. By analyzing transcriptome of enzalutamide-resistant prostate cancer cells, we fou...

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Detalles Bibliográficos
Autores principales: Xia, Jia, Zhang, Jiahui, Wang, Liangzhe, Liu, Hailong, Wang, Jie, Liu, Junyan, Liu, Zhaoqian, Zhu, Yingjian, Xu, Yingjie, Yang, Wen, Yu, Yongjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418603/
https://www.ncbi.nlm.nih.gov/pubmed/34482382
http://dx.doi.org/10.1038/s41419-021-04126-4