Targeting cancer cell plasticity by HDAC inhibition to reverse EBV-induced dedifferentiation in nasopharyngeal carcinoma

Application of differentiation therapy targeting cellular plasticity for the treatment of solid malignancies has been lagging. Nasopharyngeal carcinoma (NPC) is a distinctive cancer with poor differentiation and high prevalence of Epstein-Barr virus (EBV) infection. Here, we show that the expression...

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Detalles Bibliográficos
Autores principales: Xie, Jiajun, Wang, Zifeng, Fan, Wenjun, Liu, Youping, Liu, Fang, Wan, Xiangbo, Liu, Meiling, Wang, Xuan, Zeng, Deshun, Wang, Yan, He, Bin, Yan, Min, Zhang, Zijian, Zhang, Mengjuan, Hou, Zhijie, Wang, Chunli, Kang, Zhijie, Fang, Wenfeng, Zhang, Li, Lam, Eric W-F, Guo, Xiang, Yan, Jinsong, Zeng, Yixin, Chen, Mingyuan, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418605/
https://www.ncbi.nlm.nih.gov/pubmed/34482361
http://dx.doi.org/10.1038/s41392-021-00702-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418605/
https://www.ncbi.nlm.nih.gov/pubmed/34482361
http://dx.doi.org/10.1038/s41392-021-00702-4

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