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Notch1/TAZ axis promotes aerobic glycolysis and immune escape in lung cancer

Oncogenic signaling pathway reprograms cancer cell metabolism to promote aerobic glycolysis in favor of tumor growth. The ability of cancer cells to evade immunosurveillance and the role of metabolic regulators in T-cell functions suggest that oncogene-induced metabolic reprogramming may be linked t...

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Detalles Bibliográficos
Autores principales: Xie, Mian, Fu, Xin-ge, Jiang, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418606/
https://www.ncbi.nlm.nih.gov/pubmed/34482375
http://dx.doi.org/10.1038/s41419-021-04124-6