Proteomic signatures of myeloid derived suppressor cells from liver and lung metastases reveal functional divergence and potential therapeutic targets

Myeloid-derived suppressor cells (MDSCs) promote immunosuppressive activities in the tumor microenvironment (TME), resulting in increased tumor burden and diminishing the anti-tumor response of immunotherapies. While primary and metastatic tumors are typically the focal points of therapeutic develop...

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Detalles Bibliográficos
Autores principales: DaSilva, Nicholas A., Barlock, Benjamin J., Guha, Prajna, Ghosh, Chandra C., Trebino, Catherine E., Camberg, Jodi L., Katz, Steven C., Rowley, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418613/
https://www.ncbi.nlm.nih.gov/pubmed/34482371
http://dx.doi.org/10.1038/s41420-021-00621-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418613/
https://www.ncbi.nlm.nih.gov/pubmed/34482371
http://dx.doi.org/10.1038/s41420-021-00621-x

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