Gambogic Acid Inhibits Wnt/β-catenin Signaling and Induces ER Stress-Mediated Apoptosis in Human Cholangiocarcinoma

OBJECTIVE: Gambogic acid (GA) has been reported to induce apoptosis in cholangiocarcinoma (CCA) cell lines. However, the molecular mechanisms underlying its anti-cancer activity remain poorly understood. This study was aimed to investigate GA’s effect on human CCA cell lines, KKU-M213 and HuCCA-1, a...

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Detalles Bibliográficos
Autores principales: Suksen, Kanoknetr, Janpipatkul, Keatdamrong, Reabroi, Somrudee, Anantachoke, Natthinee, Reutrakul, Vichai, Chairoungdua, Arthit, Thongon, Natthakan, Bhukhai, Kanit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: West Asia Organization for Cancer Prevention 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418851/
https://www.ncbi.nlm.nih.gov/pubmed/34181351
http://dx.doi.org/10.31557/APJCP.2021.22.6.1913

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418851/
https://www.ncbi.nlm.nih.gov/pubmed/34181351
http://dx.doi.org/10.31557/APJCP.2021.22.6.1913

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