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Epidermal Growth Factor Receptor Gene Mutation Detection in Histology and Cytology Specimens of Primary Lung Adenocarcinoma: Immunohistochemistry Versus the Molecular Method
BACKGROUND: Epidermal growth factor receptor (EGFR) gene in lung adenocarcinoma is associated with good clinical response to EGFR-tyrosine kinase therapy. The two most common EGFR gene mutations, representing 80 to 90%, are the E746-A750 deletion in exon 19 and the L858R point mutation in exon 21. M...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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West Asia Organization for Cancer Prevention
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418853/ https://www.ncbi.nlm.nih.gov/pubmed/34181354 http://dx.doi.org/10.31557/APJCP.2021.22.6.1935 |