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SARS‐CoV‐2 sculpts the immune system to induce sustained virus‐specific naïve‐like and memory B‐cell responses

OBJECTIVES: SARS‐CoV‐2 infection induces virus‐reactive memory B cells expressing unmutated antibodies, which hints at their emergence from naïve B cells. Yet, the dynamics of virus‐specific naïve B cells and their impact on immunity and immunopathology remain unclear. METHODS: We longitudinally pro...

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Detalles Bibliográficos
Autores principales: de Campos‐Mata, Leire, Tejedor Vaquero, Sonia, Tachó‐Piñot, Roser, Piñero, Janet, Grasset, Emilie K, Arrieta Aldea, Itziar, Rodrigo Melero, Natalia, Carolis, Carlo, Horcajada, Juan P, Cerutti, Andrea, Villar‐García, Judit, Magri, Giuliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8418925/
https://www.ncbi.nlm.nih.gov/pubmed/34504693
http://dx.doi.org/10.1002/cti2.1339