Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation

Modulation of the innate immune system is emerging as a promising therapeutic strategy against Alzheimer's disease (AD). However, determinants of a beneficial therapeutic effect are ill-understood. Thus, we investigated the potential of 18 kDa translocator protein positron-emission-tomography (...

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Detalles Bibliográficos
Autores principales: Biechele, Gloria, Blume, Tanja, Deussing, Maximilian, Zott, Benedikt, Shi, Yuan, Xiang, Xianyuan, Franzmeier, Nicolai, Kleinberger, Gernot, Peters, Finn, Ochs, Katharina, Focke, Carola, Sacher, Christian, Wind, Karin, Schmidt, Claudio, Lindner, Simon, Gildehaus, Franz-Josef, Eckenweber, Florian, Beyer, Leonie, von Ungern-Sternberg, Barbara, Bartenstein, Peter, Baumann, Karlheinz, Dorostkar, Mario M., Rominger, Axel, Cumming, Paul, Willem, Michael, Adelsberger, Helmuth, Herms, Jochen, Brendel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419052/
https://www.ncbi.nlm.nih.gov/pubmed/34522221
http://dx.doi.org/10.7150/thno.64022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419052/
https://www.ncbi.nlm.nih.gov/pubmed/34522221
http://dx.doi.org/10.7150/thno.64022

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