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Angiotensin IV attenuates diabetic cardiomyopathy via suppressing FoxO1-induced excessive autophagy, apoptosis and fibrosis

Rationale: The rennin-angiotensin-aldosterone system (RAAS) plays a critical role in the pathogenesis of diabetic cardiomyopathy, but the role of a member of RAAS, angiotensin IV (Ang IV), in this disease and its underlying mechanism are unclear. This study was aimed to clarify the effects of Ang IV...

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Detalles Bibliográficos
Autores principales: Zhang, Meng, Sui, Wenhai, Xing, Yanqiu, Cheng, Jing, Cheng, Cheng, Xue, Fei, Zhang, Jie, Wang, Xiaohong, Zhang, Cheng, Hao, Panpan, Zhang, Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419053/
https://www.ncbi.nlm.nih.gov/pubmed/34522203
http://dx.doi.org/10.7150/thno.48561