Exosomal miR-21 from tubular cells contributes to renal fibrosis by activating fibroblasts via targeting PTEN in obstructed kidneys

Rationale: Ureteral obstruction-induced hydronephrosis is associated with renal fibrosis and progressive chronic kidney disease (CKD). Exosome-mediated cell-cell communication has been suggested to be involved in various diseases, including renal fibrosis. However, little is known regarding how exos...

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Detalles Bibliográficos
Autores principales: Zhao, Sheng, Li, Wei, Yu, Weimin, Rao, Ting, Li, Haoyong, Ruan, Yuan, Yuan, Run, Li, Chenglong, Ning, Jinzhuo, Li, Siqi, Chen, Wu, Cheng, Fan, Zhou, Xiangjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419054/
https://www.ncbi.nlm.nih.gov/pubmed/34522205
http://dx.doi.org/10.7150/thno.62820

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419054/
https://www.ncbi.nlm.nih.gov/pubmed/34522205
http://dx.doi.org/10.7150/thno.62820

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