Deficiency of the X-inactivation escaping gene KDM5C in clear cell renal cell carcinoma promotes tumorigenicity by reprogramming glycogen metabolism and inhibiting ferroptosis

Background: Clear cell renal cell carcinoma (ccRCC) is characterized by glycogen-laden, unexplained male predominance, and frequent mutations in the Von Hippel-Lindau (VHL) gene and histone modifier genes. Besides, poor survival rates of ccRCC patients seem to be associated with up-regulation of the...

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Detalles Bibliográficos
Autores principales: Zheng, Qian, Li, Pengfei, Zhou, Xin, Qiang, Yulong, Fan, Jiachen, Lin, Yan, Chen, Yurou, Guo, Jing, Wang, Fan, Xue, Haihua, Xiong, Jie, Li, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419058/
https://www.ncbi.nlm.nih.gov/pubmed/34522206
http://dx.doi.org/10.7150/thno.60233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419058/
https://www.ncbi.nlm.nih.gov/pubmed/34522206
http://dx.doi.org/10.7150/thno.60233

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