Inhibition of BUB1 suppresses tumorigenesis of osteosarcoma via blocking of PI3K/Akt and ERK pathways

Osteosarcoma (OS) is a primary malignant bone tumour that mainly affects teenagers, with patients displaying poor prognosis. Budding uninhibited by benzimidazoles 1 (BUB1), a type of serine/threonine kinase that is linked to pro‐tumorigenic phenomena, has not been well studied in OS. Hence, this stu...

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Detalles Bibliográficos
Autores principales: Huang, Zhen, Wang, Shenglin, Wei, Hongxiang, Chen, Hui, Shen, Rongkai, Lin, Renqin, Wang, Xinwen, Lan, Wenbin, Lin, Rongjin, Lin, Jianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419163/
https://www.ncbi.nlm.nih.gov/pubmed/34337852
http://dx.doi.org/10.1111/jcmm.16805

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8419163/
https://www.ncbi.nlm.nih.gov/pubmed/34337852
http://dx.doi.org/10.1111/jcmm.16805

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